• br Results On the th day

  2020-08-10

  

  Results On the 8th day, the horizontal (Fig. 1) and vertical locomotor activity (Fig. 2) and the dorsal (Fig. 3) and tranylcypromine striatal dopamine release (Fig. 4) increased significantly in nicotine-treated rats, compared with the saline-treated rats. Tukey post-hoc test revealed the follow

• We performed three baseline scans in two baboons and one

  2020-08-10

  

  We performed three baseline scans in two baboons and one blocking study by administering 1 mg/kg (i.v) meloxicam 30 min prior to [C]TMI injection (injected activity 175.75 ± 18.5 MBq, mass of unlabeled TMI 8-CPT-2Me-cAMP, sodium salt barrier (BBB) and retained in brain with a somewhat heterogeneous

• JSH-23 br Related work Goal of

  2020-08-10

  

  Related work Goal of this section is to show related work focused on methods useful to assess the reliability of clustered COTS-based systems. Connelly et al. [1] propose an approach to delineate safety assurance for the use of COTS OS in safety-related applications, which must fall in SIL2. Th

• br Materials and methods br Results br

  2020-08-10

  

  Materials and methods Results Discussion Adiponectin is one of the most studied adipocytokines. Its release from adipocytes is down-regulated in obesity and other adverse metabolic conditions leading to decreased serum concentrations (Turer and Scherer, 2012). Several factors and conditions

• Several reasons may explain that other studies

  2020-08-10

  

  Several reasons may explain that other studies using PDE-5-Is yielded negative or contradictory results [30], [31], [32]. Lee [30] applied 50mg sildenafil to seven patients with liver cirrhosis. NO and cGMP in the hepatic 1602 significantly increased, hepatic and pulmonary resistance decreased, an

• In recent years there has been much interest within

  2020-08-10

  

  In recent years, there has been much interest within the endothelin community regarding the possibility that ETA and ETB receptors may form homo- and heterodimers. Heterodimerization of endothelin receptors may provide an explanation for the results mentioned in the previous paragraph and might also

• Cy7 NHS ester (non-sulfonated) Brg is a core unit of BAF

  2020-08-10

  

  Brg1 is a core unit of BAF complex and is required for the self-renewal and pluripotency of ESCs (Ho and Crabtree, 2010). We confirmed the interaction of DPF2 and BRG1 by immunoprecipitation and showed that these proteins extensively co-localize in the genome. Although both Brg1 and Dpf2 positively

• Enolase is an example of a

  2020-08-10

  

  Enolase is an example of a moonlighting protein that displays multiple biological actions, including plasminogen, laminin, fibronectin, mucin and cytokeratin binding properties. It has also been described as a complement-evasion protein and as a protein capable of inducing neutrophil trap formation.

• In the present study real

  2020-08-10

  

  In the present study, real-time polymerase chain reaction also confirmed that gene expressions of RT1 class II, locus Bb (RT1-Bb) was up-regulated and Spi-B transcription factor (Spib) was downregulated at day 3 after the VMH lesions. These two genes work as one of immune responses. RT1-Bb controls

• Introduction Cognitive impairment is a core stable

  2020-08-09

  

  Introduction Cognitive impairment is a core, stable feature of schizophrenia that limits patient functioning and well-being (Keefe and Harvey, 2012) and associates with poor functional outcome (Fervaha et al., 2014, Kontaxaki et al., 2014). Studies also indicate that cognitive deficits occur prior

• Misoprostol Astrocytes play a key role in the brain

  2020-08-08

  

  Astrocytes play a key role in the brain, as these cells are involved in fluid, ion, pH, and neurotransmitter homeostasis, synapse function, energy and metabolism and blood-brain barrier (BBB) maintenance (Sofroniew and Vinters, 2010). PA is able to activate different damaging responses in astrocytes

• br Materials and methods br Results br Discussion RHA P

  2020-08-08

  

  Materials and methods Results Discussion RHA-P is a bacterial α-l-rhamnosidase recently isolated from the microorganism Novosphingobium sp. PP1Y [35]. This enzyme is an inverting glycosidase, belonging to the GH106 family, for which an initial biochemical characterization has highlighted an

• br ET Receptor Blockade in Chronic Kidney

  2020-08-08

  

  ET-Receptor Blockade in Chronic Kidney Disease Receptor antagonists have emerged as the only strategy in the clinic for blocking the unwanted actions of ET-1. To date, no alternative strategies, such as inhibitors of ET converting UNC2881 mg or combined endothelin-converting enzyme (ECE)/neutral

• Oxysterols modulate the immune responses and as such could b

  2020-08-08

  

  Oxysterols modulate the immune responses and as such could be effectors of the tumor environment: 25-OHC impairs IgA production in B-lymphocytes [26] and induces the secretion of the proinflammatory and angiogenic cytokine IL-8 [27], [28]. Of note, oxysterols (in particular 7α,25-OHC) are potent che

• E ligases have been associated with a number of pathogenic

  2020-08-08

  

  E3 ligases have been associated with a number of pathogenic mechanisms. Mutations in the E3 ligases MDM2, BRCA1, TRIMs, and Parkin have been linked to multiple cancers and neurodegenerative diseases (Fakharzadeh et al., 1991, Hatakeyama, 2011, Welcsh and King, 2001), and MDM2-p53 interaction inhibit

15556 records 791/1038 page Previous Next First page 上5页 791792793794795 下5页 Last page