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SRSF is a member of Arginine Serine
2021-12-02
SRSF4 is a member of Arginine-Serine-rich (SR) protein family, that is essential for constitutive splicing and regulates alternative splicing [14]. SR proteins include one or two RNA recognition motifs (RRM) at their amino terminus and RS domains at carboxyl terminus [[15], [16], [17], [18]]. Wherea
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There are limited studies on antibody
2021-12-02
There are limited studies on antibody responses against HIV-1 integrase antigen. According to previous studies, almost 5 percent of individuals infected with HIV never raise anti-integrase GSK2334470 (Rikhtegaran Tehrani et al., 2015; Chang et al., 1985). If this rate is identical in individuals inf
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NCSs are helical proteins containing four EF
2021-12-02
NCSs are α-helical proteins containing four EF-hand motifs with EF1 being incapable of Ca-binding throughout the family (atomic-resolution structure was firstly resolved for recoverin [5]; for review on NCS structure, see [6]). Some of the NCS proteins (i.e. recoverin and KChIP3) have two while othe
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Both plant hormones and some second messengers are involved
2021-12-02
Both plant hormones and some second messengers are involved in Fe-deficiency-related responses in plants (Kobayashi and Nishizawa, 2012). Among these second messengers, nitric oxide (NO) accumulation was induced by Fe deficiencies in tomato and Arabidopsis roots, and it acts as the downstream signal
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NCT-503 australia br Materials and methods br Results br
2021-12-02
Materials and methods Results Discussion To understand the molecular basis for how ghrelin secretion is regulated at the cellular level, we identified the full repertoire of 7TM receptors and G proteins in gastric ghrelin NCT-503 australia and functionally characterized the majority of the
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In addition to vertebrate species
2021-12-02
In addition to vertebrate species, GnRH has been identified in invertebrates, such as in the Protochordate Ciona intestinalis (Powell et al., 1996; Adams et al., 2003), the decapods mollusk Octopus vulgaris (Iwakoshi et al., 2002), the gastropod mollusk, the sea hare Aplysia californica (Zhang et al
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According to the aforementioned preclinical and clinical dat
2021-12-01
According to the aforementioned preclinical and clinical data, GHS-R1a blockade appears to be a potential pharmacological approach to treat AUD. Given that GHS-R1a has high constitutive (ligand-independent) activity, inverse agonism of the receptor may exert more potent and desirable effects than pu
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br Materials and method http www apexbt com media
2021-12-01
Materials and methods Results Discussion This study provide for the first time a report on GALP in fish, providing new information towards the distribution and functional characterization of the galaninergic system in these vertebrates. Our studies show the detailed neuroanatomical distribu
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The present study demonstrates that SNAP exhibits a toxic
2021-12-01
The present study demonstrates that SNAP 37889 exhibits a toxic effect to these specific cell types, which is independent of endogenous expression of GAL receptor subtypes and leads to apoptosis. This conclusion is based on our findings that, although HMCB, HL-60 and SH-SY5Y cell lines differ in GAL
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Bile acids BAs are detergent like amphipathic molecules synt
2021-12-01
Bile acids (BAs) are detergent-like amphipathic molecules synthesized from cholesterol in the liver, stored in the gallbladder, and released into the intestine after food intake in order to facilitate the IFN-alpha 1, human recombinant protein of dietary lipids and liposoluble vitamins. BAs travel
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The mechanisms underlying the inhibitory effects of n
2021-12-01
The mechanisms underlying the inhibitory effects of n-3 FAs on neoplasia have not been completely elucidated. Until recently, the emphasis has been on the ability of n-3 FAs to compete for the pathways that lead to the synthesis of pro-inflammatory eicosanoids from arachidonic acid, an n-6 FA, there
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HIV incidence is often determined
2021-12-01
HIV incidence is often determined by following cohorts of HIV-uninfected individuals and quantifying the rate of new HIV infections. HIV incidence can also be estimated using a cross-sectional study design, using laboratory assays to identify individuals who are likely to have recent HIV infection.
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br Conflict of interest statement br
2021-12-01
Conflict of interest statement References and recommended reading Papers of particular interest, published within the period of review, have been highlighted as: Acknowledgements We thank Urann Chan for assistance with the figures. This work was supported in part by National Institutes of
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Although the presence of histamine
2021-12-01
Although the presence of histamine-secreting bacteria has been well documented in foods, their presence within the human gut microbiota has not been investigated in detail. We recently performed an analysis of fecal samples from 161 volunteers to quantify the presence of bacterial HDC, using primers
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The first suggestion that histamine may play a role
2021-12-01
The first suggestion that histamine may play a role in memory consolidation was from Almeida and Izquierdo (de Almeida & Izquierdo, 1986) who showed that the immediate posttraining intracerebroventricular (i.c.v.) administration of 1–10ng of the drug were found to enhance the retention of one-trial
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