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Preclinical studies have shown that adipocytes
2019-05-29

Preclinical studies have shown that adipocytes and MSCs play an important role in migration and dissemination of cancer cyp450 inhibitors [55,56]. Concerning osteosarcoma, one publication has reported that human MSCs injected through the caudal vein of mice bearing Saos-2- induced an increase in tu
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br Genetic basis for atrial
2019-05-29

Genetic basis for atrial standstill Genetic basis of conduction block Genes involved in cardiac development and bradycardia Development of the CCS is a complex biological process with the potential to be wrought with problems. Several transcription factors, including homeodomain proteins an
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br Control of visceral leishmaniasis
2019-05-28

Control of visceral leishmaniasis requires access to low-cost, safe, and effective treatment. Amphotericin causes infusion-related fever, rigor, and nephrotoxicity, limiting its use. Ambisome—a liposomal amphotericin manufactured by Gilead—is better tolerated and is effective as a single dose. How
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Al ser verdad lo anterior no lo es menos
2019-05-28

Al ser verdad lo anterior, no lo es menos que la cultura asentada en tiempos coloniales, a diferencia de la que llegó en los primeros tiempos de la conquista, respondía a la relativa ignorancia del mundo clásico en España, sobre todo del griego. Fue el país donde más se leyeron sus autores en traduc
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br The study by Jesse Berman and colleagues
2019-05-28

The study by Jesse Berman and colleagues published in is the first to systematically analyse the risk of hospital admissions and mortality associated with drought periods in the USA. As the authors state, this is an understudied topic, but of great concern in the USA and globally as climate chang
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The electrocardiogram showed narrow QRS complex regular tach
2019-05-28

The electrocardiogram showed narrow QRS complex regular tachycardia, which was terminated by rapid injection of adenosine triphosphate. During the tachycardia, the P wave was not identifiable and was likely hidden completely in the QRS complex (Fig. 1). As the patient desired complete cure of the ta
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br Perioperative risk assessment of
2019-05-28

Perioperative risk assessment of thromboembolism The current thromboembolic risk stratification is largely based on indirect evidence from studies outside of the perioperative setting involving patients with a mechanical alkaline phosphatase inhibitor valve, chronic atrial fibrillation or venous
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br Introduction Sudden cardiac death SCD
2019-05-28

Introduction Sudden cardiac death (SCD) in patients with low ventricular function remains a substantial problem despite improved medical therapies [1–3]. Many patients require antiarrhythmic drugs to prevent recurrent arrhythmias and reduce the number of shocks from implanted cardioverter-defibri
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Early recognition of ICD lead malfunction
2019-05-28

Early recognition of ICD lead malfunction is desirable to prevent the life-threatening consequences of lead failure. Recent reports indicate that the majority of patients with ICD lead failure experience inappropriate ICD therapies, often as the presenting problem [4,6]. Regular device interrogation
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br Conclusions It is now
2019-05-28

Conclusions It is now clear that a number of GS-9620 are involved in inherited bradyarrhythmia. Recent genetic studies have demonstrated that inherited arrhythmia is attributable to many genes with diverse functions. While the precise underlying mechanisms remain to be elucidated; these genetic d
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The potential improvement in management of patients can be
2019-05-27

The potential improvement in management of patients can be evidenced by a paper comparing baseline symptom severity over two time frames by Khan et al.[17]. Baseline edmonton symptom assessment system (ESAS) scores reported by patients seen from 2006 to 2009 were found to exhibit significant improve
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RANK RANKL The RANK RANKL signaling pathway is
2019-05-27

RANK/RANKL: The RANK/RANKL signaling pathway is a critical component of both normal and malignant bone remodeling. RANK is a transmembrane signaling receptor and a member of the tumor necrosis receptor (TNF) superfamily that is found on the surface of OCL precursors [43,44]. RANK ligand (RANKL) is e
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En otros casos como en de scar de
2019-05-27

En otros casos, como en de Óscar de Pablo (1979), predomina el referente histórico como una nimesulide para desarrollar tramas narrativas muy complejas, donde puede mezclarse poesía y reflexión social; en “Nadie (que yo conozca) es Tolomeo III”, aprovecha la imagen de un faraón egipcio del siglo i
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br Diarrhoeal diseases are the second most
2019-05-27

Diarrhoeal diseases are the second most common cause of deaths of children, killing more than 1·5 million children annually and infecting billions more. The recently released Global Action Plan for Pneumonia and Diarrhoea (GAPPD) is a comprehensive strategy document outlining plans to end preventa
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Unfortunately no trends in retention in care were presented
2019-05-27

Unfortunately, no trends in retention in care were presented by Nsanzimana and colleagues, and the method used to estimate life expectancy—the abridged life table method—is not well suited to answering questions about trends in quality of care, because it fxr agonist allows little scope for multiva
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